Paramagnetic rim lesions predict greater long-term relapse rates and clinical progression over 10 years.
Jack A ReevesMaryam MohebbiTaylor WicksFahad SalmanAlexander BartnikDejan JakimovskiNiels P BergslandFerdinand SchweserBianca Weinstock-GuttmanMichael G DwyerRobert ZivadinovPublished in: Multiple sclerosis (Houndmills, Basingstoke, England) (2024)
PRLs are a marker of aggressive ongoing disease inflammatory activity, including more frequent future clinical relapses and greater long-term, relapse-independent disability progression.