Animal experimental research assessing urogynecologic surgical mesh implants: Outcome measures describing the host response, a systematic review and meta-analysis.
Kim W J VerhorstertAksel N GuddeBrita S KortzJacqueline LimpensJan-Paul W R RooversCarlijn R HooijmansZeliha GulerPublished in: Neurourology and urodynamics (2021)
The host response significantly differs in animals after vaginal mesh implantation compared to control animals, both pro- and anti-inflammatory. However, we observed a paucity in the uniformity of reported outcomes. For future animal studies, we propose the development of a core outcome set, which ideally predicts the host response in women.