Circulating microRNAs can predict chemotherapy-induced toxicities in patients being treated for primary breast cancer.

Matthew G DaveyRay AbbasEoin P KerinMaire Caitlin CaseyAndrew McGuireRonan M WaldronHelen M HeneghanJohn NewellAilbhe M McDermottMaccon M KeaneAoife J LoweryNicola MillerMichael J Kerin

Published in: Breast cancer research and treatment (2023)

This is the first study which illustrates the value of measuring circulatory miRNA to predict patient-specific toxicities to NAC. These results support the ideology that circulatory miRNAs are biomarkers with utility in predicting chemotherapy toxicity as well as treatment response.

Keyphrases

chemotherapy induced
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
extracorporeal membrane oxygenation
transcription factor
peritoneal dialysis
squamous cell carcinoma
patient reported outcomes
young adults
radiation therapy
patient reported