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Evolutionary dynamics of pseudoautosomal region 1 in humans and great apes.

Juraj BergmanMikkel Heide Schierup
Published in: Genome biology (2022)
Our study provides an unprecedented quantification of population genetic forces governing PAR1 biology across extant and extinct hominids. PAR1 evolutionary dynamics are predominantly governed by recombination processes with a strong impact on mutation patterns across all species.
Keyphrases
  • genome wide
  • dna damage
  • dna repair
  • copy number
  • oxidative stress
  • genetic diversity