Antimicrobial activity of an aspartic protease from Salpichroa origanifolia fruits.
M E DíazG F RochaF KiseA M RossoM G GuevaraMónica G ParisiPublished in: Letters in applied microbiology (2018)
This study provides insights into the antimicrobial activity of an aspartic protease isolated from Salpichroa origanifolia fruits on plant and human pathogens. The proteinase inhibited Fusarium solani and Staphylococcus aureus in a dose-dependent manner due to the alteration of the cell plasma membrane barrier but not due to its proteolytic activity. Antimicrobial activity of salpichroin suggests its potential applications as an important tool for the control of pathogenic micro-organisms affecting humans and crops of economic interest. Therefore, it would represent a new alternative to avoid the problems of environmental pollution and antimicrobial resistance.
Keyphrases
- antimicrobial resistance
- staphylococcus aureus
- endothelial cells
- mental health
- heavy metals
- human health
- gram negative
- single cell
- risk assessment
- particulate matter
- life cycle
- cell therapy
- induced pluripotent stem cells
- stem cells
- health risk assessment
- escherichia coli
- cystic fibrosis
- climate change
- methicillin resistant staphylococcus aureus