Differential lung inflammation and injury with tobacco smoke exposure in Wistar Kyoto and spontaneously hypertensive rats.

Alexa K PhamChing-Wen WuXing QiuJingyi XuSuzette Smiley-JewellDale UyeminamiPriya UpadhyayDewei ZhaoKent E Pinkerton

Published in: Inhalation toxicology (2020)

The progressive tobacco smoke exposure contributes to persistent lung injury and inflammation that can be significantly enhanced by rat strain susceptibility in the genesis of COPD.

Keyphrases

oxidative stress
chronic obstructive pulmonary disease
multiple sclerosis
lung function