Login / Signup

KDM4C represses liver fibrosis by regulating H3K9me3 methylation of ALKBH5 and m6A methylation of snail1 mRNA.

Hua Ying ZhouBing Qing WangMeng Xuan ChenYi Fan WangYong Fang JiangJing Ma
Published in: Journal of digestive diseases (2024)
KDM4C decreases H3K9me3 methylation to upregulate ALKBH5 and subsequently inhibits snail1, ultimately impeding liver fibrosis.
Keyphrases
  • liver fibrosis
  • genome wide
  • epithelial mesenchymal transition
  • dna methylation
  • binding protein
  • signaling pathway