Prevalence of germline variants in inflammatory breast cancer.
Huma Q RanaRosalba SaccaChristine DroganStephanie GutierrezEmily SchlosnagleMeredith M ReganVirginia SpeareHolly LaDucaJill DolinskyJudy E GarberBeth A OvermoyerPublished in: Cancer (2019)
The prevalence and diversity of germline genetic mutations among patients with IBC suggest that further studies should be performed to assess the role of inherited mutations in IBC carcinogenesis in comparison with non-IBC breast cancer. Since IBC has a high metastatic potential associated with poor prognostic outcomes, proposed future studies may also inform targeted treatment options.