Metabolic and cardiovascular benefits and risks of 4-hydroxy guanabenz hydrochloride: α 2 -adrenoceptor and trace amine-associated receptor 1 ligand.

with weight reduction and the amelioration of metabolic disturbances, remains an unresolved matter necessitating further investigation. Undoubtedly, the fact that 4-OH-Guanabenz is a metabolite of a well-known drug has considerable importance, which is beneficial from an economic point of view and towards its further development as a drug candidate.