Association between bisphosphonate use and stroke risk: a meta-analysis.
Shu-Man LinJhe-Yi LinYu-Kang TuChih-Hsing WuCarol Chiung-Hui PengKashif M MunirKhulood BukhariKory JaggonYunting FuChing-Hui LohHuei-Kai HuangPublished in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2023)
Our results suggest that bisphosphonate use is associated with a lower risk of stroke. However, the current evidence does not lead to a definite conclusion due to the borderline statistical significance and high between-study heterogeneity. Future studies, especially RCTs, are necessary to assess causality.