RUNX1 mutations promote leukemogenesis of myeloid malignancies in ASXL1-mutated leukemia.

Rabindranath BeraMing-Chun ChiuYing-Jung HuangTung-Huei LinMing-Chung KuoLee-Yung Shih

Published in: Journal of hematology & oncology (2019)

The present study demonstrated the biological and functional evidence for the critical role of RUNX1-MT in ASXL1-mutated leukemia in the pathogenesis of myeloid malignancies.

Keyphrases

acute myeloid leukemia
bone marrow
transcription factor