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A mouse model for the study of transplanted bone marrow mesenchymal stem cell survival and proliferation in lumbar spinal fusion.

Ioan A LinaWataru IshidaJason A LiauwSheng-Fu L LoBenjamin D ElderAlexander Perdomo-PantojaDebebe TheodrosTimothy F WithamChristina Holmes
Published in: European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society (2018)
By enabling the tracking of transplanted bone marrow-derived cells during spinal fusion in vivo, this mouse model will be integral to developing a deeper understanding of the biological processes underlying spinal fusion in future studies. These slides can be retrieved under Electronic Supplementary Material.
Keyphrases
  • mouse model
  • bone marrow
  • mesenchymal stem cells
  • spinal cord
  • induced apoptosis
  • signaling pathway
  • umbilical cord
  • cell cycle arrest
  • stem cells
  • spinal cord injury
  • cell death
  • current status
  • oxidative stress