Two sides of the same coin: the N-terminal and the receptor binding domains of SARS-CoV-2 Spike.
Massimo CiccozziStefano PascarellaPublished in: Future virology (2023)
The SARS-CoV-2 Spike receptor binding domain and N-terminal domain interact with each other in an intricate mechanism. Mutations modulate the interplay between the Spike and host molecules. This editorial comments on the intricacies of SARS-CoV-2 Spike interactions.