Role of PAR1 -506 deletion/insertion polymorphism in primary sclerosing cholangitis.
Bettina LanghansSandra KalthoffTaotao ZhouTobias J WeismüllerHenrike LenzenHans Dieter NischalkeChristian P StrassburgPhilipp LutzLeona DoldPublished in: Hepatology research : the official journal of the Japan Society of Hepatology (2024)
Our study shows that PAR1 -506 Ins is significantly more frequent in people with PSC. As PAR1 -506 Ins allele carriers tended to have a shorter transplant-free survival, PAR1 might play a role in the development and course of PSC.
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