Azithromycin to Prevent Sepsis or Death in Women Planning a Vaginal Birth.
Alan T N TitaWaldemar A CarloElizabeth M McClureMusaku MwenechanyaElwyn ChombaJennifer J Hemingway-FodayAvinash KaviMrityunjay C MetgudShivaprasad S GoudarRichard DermanAdrien LokangakaAntoinette TshefuMelissa BausermanCarl BosePoonam ShivkumarManju WaikarArchana PatelPatricia L HibberdPaul NyongesaFabian EsamaiOsayame A EkhaguereSherri BucherSaleem JessaniShiyam S TikmaniSarah SaleemRobert L GoldenbergSk M BillahRuth LennoxRashidul HaqueWilliam PetriLester FigueroaManolo MazariegosNancy F KrebsJanet L MooreTracy L NolenMarion Koso-Thomasnull nullPublished in: The New England journal of medicine (2023)
Among women planning a vaginal delivery, a single oral dose of azithromycin resulted in a significantly lower risk of maternal sepsis or death than placebo but had little effect on newborn sepsis or death. (Funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development and others; A-PLUS ClinicalTrials.gov number, NCT03871491.).