Second-hand smoke and NFE2L2 genotype interaction increases paediatric asthma risk and severity.
Elisabet JohanssonLisa J MartinHua HeXiaoting ChenMatthew T WeirauchJohn W KronerGurjit K Khurana HersheyJocelyn M BiaginiPublished in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2021)
Our study provides evidence that NFE2L2 genotype interacts with SHS exposure to affect both asthma risk and severity in children and identifies a population of children at increased risk of asthma development.