Population Pharmacokinetics and Dose Optimization of Ceftazidime and Imipenem in Patients with Acute Exacerbations of Chronic Obstructive Pulmonary Disease.

Thu-Minh NguyenThu-Hue NgoTruong Thanh Tuan Dinh-Hoa VuDinh-Chi LeNgan-Binh VuTuyet-Nga CanNguyen Hoang AnhThu-Phuong PhanFrançoise Van BambekeCéline VidaillacQuy-Chau Ngo

Published in: Pharmaceutics (2021)

This study describes a novel and versatile three-level dosing algorithm based on patients' renal function and characteristic of the infective pathogen to explore ceftazidime and imipenem optimal regimen for AECOPD.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
chronic obstructive pulmonary disease
chronic kidney disease
machine learning
gram negative
deep learning
candida albicans
patient reported outcomes
multidrug resistant