Methadone for Cancer Pain in Pediatric End-of-Life Care.
Elizabeth A HallHannah E SauerCatherine HabashyDoralina L AnghelescuPublished in: The American journal of hospice & palliative care (2020)
In patients with pediatric cancer who are nearing the end of life, methadone is a valuable adjunctive therapy to treat nociceptive and neuropathic pain and to prevent opioid-induced hyperalgesia and opioid tolerance. An individualized approach to dosage and route should be considered based on specific clinical circumstances.