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The role and mechanism of engineered nanovesicles derived from hair follicle mesenchymal stem cells in the treatment of UVB-induced skin photoaging.

Zhounan JiangHanxiao ChengXifei QianJingyi TuChongxiang FanYirui PanZhiwei LinJinyang ChenXiangsheng WangJufang Zhang
Published in: Journal of cosmetic dermatology (2024)
Conclusively, the anti-photoaging properties of HFMSC-CNVs were confirmed both in vivo and in vitro. HFMSC-CNVs exert anti-photoaging effects by alleviating cell cycle arrest, decreasing cellular senescence and macrophage infiltration, promoting cell proliferation and extracellular matrix (ECM) production, and reducing oxidative stress by increasing the activity of antioxidant enzymes.
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