Monitoring dynamic pre-crystallization aggregation processes in solution by VT-DOSY-NMR spectroscopy.

Andreas MixJan-Hendrik LammJan SchwabedissenErich GebelHans-Georg StammlerNorbert W Mitzel

Published in: Chemical communications (Cambridge, England) (2022)

Equimolar mixtures of pyridine (Py) with para -halotetrafluoropyridine (BrTFP and ITFP) were investigated by VT-diffusion NMR experiments. The formation of a halogen-bond-stabilized ITFP · Py complex was detected upon cooling a solution in methylcyclohexane- d 14 to 260 K; this allows monitoring a halogen-bond-driven aggregation process preceding crystallization in solution.

Keyphrases

solid state
magnetic resonance
high resolution
ionic liquid
transition metal