Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen.
Rany M SalemJennifer N ToddErkka ValoJoanne B ColeWei-Min ChenDarrell AndrewsMarcus G PezzolesiPaul M McKeigueLinda T HirakiChengxiang QiuViji NairChen Di LiaoJing Jing CaoErkka ValoSuna Onengut-GumuscuAdam M SmilesStuart J McGurnaghanJani K HaukkaValma HarjutsaloEoin P BrennanNatalie van ZuydamEmma AhlqvistRoss DoyleTarunveer Singh AhluwaliaMaria LajerMaria F HughesJihwan ParkJan SkupienAthina SpiliopoulouAndrew LiuRajasree MenonCarine M Boustany-KariHyun M KangRobert G NelsonRonald KleinBarbara E KleinKristine E LeeXiaoyu GaoMichael MauerSilvia MaestroniMaria Luiza CaramoriIan H de BoerRachel G MillerSerena Jingchuan GuoAndrew P BorightDavid TregouetBeata GyorgyJanet K Snell-BergeonDavid M MaahsShelley B BullAngelo J CantyColin N A PalmerLars StechemesserBernhard PaulweberRaimund WeitgasserJelizaveta SokolovskaVita RovīteValdis PīrāgsEdita PrakapieneLina RadzevicieneRasa VerkauskieneNicolae Mircea PanduruLeif C GroopMark I McCarthyHarvest F GuAnna MöllstenHenrik FalhammarKerstin BrismarFinian MartinPeter RossingTina CostacouGianpaolo ZerbiniMichel MarreSamy HadjadjAmy J McKnightCarol ForsblomGareth McKayCatherine GodsonAlexander Peter MaxwellMatthias KretzlerKatalin SusztákHelen M ColhounAndrzej KrolewskiAndrew D PatersonPer-Henrik GroopStephen S RichJoel N HirschhornJose C Floreznull nullPublished in: Journal of the American Society of Nephrology : JASN (2019)
The 16 diabetic kidney disease-associated loci may provide novel insights into the pathogenesis of this condition and help identify potential biologic targets for prevention and treatment.