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Visualization of the cysteine level during Golgi stress using a novel Golgi-targeting highly specific fluorescent probe.

Xue ZhangCaiyun LiuYanan ChenXinyu CaiWenlong ShengHanchuang ZhuPan JiaZilu LiShengyun HuangBao-Cun Zhu
Published in: Chemical communications (Cambridge, England) (2020)
A novel Golgi-targeting Cys-specific fluorescent probe (Gol-Cys) was synthesized. Probe Gol-Cys is not only sufficiently sensitive to native Cys in living cells and zebrafish, but also can be used for monitoring the Cys level during Golgi stress.
Keyphrases
  • living cells
  • fluorescent probe
  • endoplasmic reticulum
  • single molecule
  • cancer therapy
  • stress induced
  • heat stress