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Clathrin coated pits as signaling platforms for Akt signaling.

Elizabeth Smythe
Published in: The Journal of cell biology (2022)
Signaling by the activated epidermal growth factor receptor (EGFR) results in diverse cell fates. In this issue, Cabral-Dias et al. (2022. J. Cell Biol.https://doi.org/10.1083/jcb.201808181) demonstrate how plasma membrane clathrin coated pits can act as a signaling platform for one branch of EGFR downstream signaling.
Keyphrases
  • epidermal growth factor receptor
  • tyrosine kinase
  • small cell lung cancer
  • single cell
  • advanced non small cell lung cancer
  • cell therapy
  • mesenchymal stem cells
  • bone marrow