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tsRNA-GlyGCC promotes colorectal cancer progression and 5-FU resistance by regulating SPIB.

Rong XuAshuai DuXinpei DengWei DuKaiying ZhangJianbo LiYingxue LuXiaoli WeiQinglong YangXiaoming Xie
Published in: Journal of experimental & clinical cancer research : CR (2024)
Our study revealed a specific tsRNA-GlyGCC-engaged pathway in CRC progression. Targeting tsRNA-GlyGCC in combination with 5-FU may provide a promising nanotherapeutic strategy for the treatment of 5-FU-resistance CRC.
Keyphrases
  • cancer therapy
  • drug delivery
  • combination therapy