Large-scale discovery of male reproductive tract-specific genes through analysis of RNA-seq datasets.

Matthew J RobertsonKatarzyna KentNathan TharpKaori NozawaLaura DeanMichelle MathewSandra L GrimmZhifeng YuChristine LégaréYoshitaka FujiharaMasahito IkawaRobert SullivanCristian CoarfaMartin M MatzukThomas X Garcia

Published in: BMC biology (2020)

Our work provides a plethora of novel testis- and epididymis-specific genes and elucidates the functional requirement of several of these genes, which is essential towards understanding the etiology of male infertility and the development of male contraceptives.

Keyphrases

rna seq
single cell
genome wide
bioinformatics analysis
genome wide identification
small molecule
high throughput
genome wide analysis
gene expression
metabolic syndrome
skeletal muscle