Combining 1H-NMR-based metabonomics and network pharmacology to dissect the mechanism of antidepression effect of Milletia speciosa Champ on mouse with chronic unpredictable mild stress-induced depression.

Zhi-Heng SuJunxiang RuanXi LiuHua ZhengJingzhou RuanYuying LuBang ChengFang WuJinxia WuXuwen LiuFangming SongZhaoni ChenHui SongYonghong LiangHongwei Guo

Published in: The Journal of pharmacy and pharmacology (2021)

This study for the first time preliminary clarified the potential antidepressive mechanism of MS and provided theoretical basis for developing MS into novel effective antidepressant.

Keyphrases

stress induced
mass spectrometry
multiple sclerosis
ms ms
magnetic resonance
major depressive disorder
high resolution
depressive symptoms
physical activity
risk assessment
solid state
climate change