Bleeding risk by intensity of anticoagulation in critically ill patients with COVID-19: A retrospective cohort study.

Rim HalabyAdam CukerJennifer YuiAndrew MatthewsElla IshaayaElizabeth TraxlerChristopher DomenicoTara CooperAnn TierneyPardis NiamiNathalie van der RijstSrinath AdusumalliJacob GutscheJay GiriSteven PuglieseTodd E H HechtAllyson M Pishko

Published in: Journal of thrombosis and haemostasis : JTH (2021)

Critically ill patients with COVID-19 had a similar bleeding risk as ORVI patients. When accounting for changes in anticoagulation that occurred in COVID-19 patients, therapeutic-intensity anticoagulation was associated with a greater risk of major bleeding compared with standard thromboprophylaxis.

Keyphrases

atrial fibrillation
venous thromboembolism
direct oral anticoagulants
end stage renal disease
newly diagnosed
ejection fraction
high intensity
chronic kidney disease
sars cov
prognostic factors
peritoneal dialysis