Role and regulation of autophagy and apoptosis by nitric oxide in hepatic stellate cells during acute liver failure.

Li JinHeng GaoJiuPing WangShuJuan YangJing WangJingFeng LiuYuan YangTaoTao YanTianyan ChenYingren ZhaoYingli He

Published in: Liver international : official journal of the International Association for the Study of the Liver (2017)

Increased nitric oxide synthases/ nitric oxide promotes apoptosis through autophagy inhibition in hepatic stellate cells during acute liver failure, providing a novel strategy for the treatment of patients with acute liver failure.

Keyphrases

liver failure
nitric oxide
cell cycle arrest
endoplasmic reticulum stress
induced apoptosis
cell death
hepatitis b virus
oxidative stress
pi k akt
signaling pathway
nitric oxide synthase
hydrogen peroxide
intensive care unit