Role of Chitinase 3-like 1 as a Biomarker in Multiple Sclerosis: A Systematic Review and Meta-analysis.
Stefano FloroTiziana CarandiniAnna Margherita PietroboniMilena Alessandra De RizElio ScarpiniDaniela GalimbertiPublished in: Neurology(R) neuroimmunology & neuroinflammation (2022)
CSF levels of CHI3L1 have a strong correlation with the MS pathologic course, in particular with the mechanism of progression of the disease; it helps to distinguish the PPMS from the RRMS. The potential role of CHI3L1 in serum needs to be further studied in the future.