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Domino Corey-Chaykovsky Reaction for One-Pot Access to Spirocyclopropyl Oxindoles.

Saumen HajraSayan RoySk Abu Saleh
Published in: Organic letters (2018)
The development of the sequential Corey-Chaykovsky reactions of isatins, spiroepoxy-, or spiroaziridine oxindoles with sulfur ylide has led to the discovery of a unique reaction mode that allows easy and direct one-pot access to a range of spirocyclopropyl oxindoles.
Keyphrases
  • small molecule
  • high throughput
  • electron transfer