Impact of HBV genotype and mutations on HBV DNA and qHBsAg levels in patients with HBeAg-negative chronic HBV infection.
L KuhnhennB JiangA KubeschJohannes VermehrenViola KnopS SusserJ DietzG CarraFabian FinkelmeierG GrammatikosS ZeuzemC SarrazinE HildtKai-Hendrik PeifferPublished in: Alimentary pharmacology & therapeutics (2018)
qHBsAg serum levels depend on the HBV genotype and together with HBV DNA levels on frequent mutations in PC, BCP and preS in HBeAg-negative patients. qHBsAg cut-offs when used as prognostic markers require genotype-dependent validation.