DPYD*2A and MTHFR C677T predict toxicity and efficacy, respectively, in patients on chemotherapy with 5-fluorouracil for colorectal cancer.

Noor Ahmed NahidMohd Nazmul Hasan ApuMd Reazul IslamSamia ShabnazSurid Mohammad ChowdhuryMaizbha Uddin AhmedZabun NaharMd Siddiqul IslamMohammad Safiqul IslamAbul Hasnat

Published in: Cancer chemotherapy and pharmacology (2017)

DPYD*2A and MTHFR C677T polymorphisms could explain 5-FU toxicity or clinical outcome in Bangladeshi colorectal patients.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
oxidative stress
prognostic factors
squamous cell carcinoma
patient reported outcomes