Public Regulatory Databases as a Source of Insight for Neuromodulation Devices Stimulation Parameters.
Doe KumsaG Karl SteinkeGregory F MolnarEric M HudakFred W MontagueShawn C KelleyDarrel F UnterekerAlan ShiBenjamin P HahnChris ConditHyowon LeeDawn BardotJose A CentenoVictor KrauthamerPavel A TakmakovPublished in: Neuromodulation : journal of the International Neuromodulation Society (2017)
Analysis of relevant entries from public regulatory databases reveals use of pig, sheep, monkey, dog, and goat animal models with deep brain, peripheral nerve, muscle and spinal cord electrode placement with a variety of stimulation durations (hours to years); frequencies (10-10,000 Hz) and magnitudes (Shannon k from below zero to 4.47). Data from located entries indicate that a feline cortical model that employs acute stimulation might have limitations for assessing tissue damage in diverse anatomical locations, particularly for peripheral nerve and spinal cord simulation.
Keyphrases
- peripheral nerve
- spinal cord
- big data
- healthcare
- spinal cord injury
- neuropathic pain
- transcription factor
- mental health
- liver failure
- skeletal muscle
- oxidative stress
- electronic health record
- drug induced
- resting state
- artificial intelligence
- ultrasound guided
- brain injury
- intensive care unit
- carbon nanotubes
- aortic dissection
- deep learning
- data analysis
- functional connectivity