Microbiome dysbiosis is associated with disease duration and increased inflammatory gene expression in systemic sclerosis skin.
Michael E JohnsonJennifer M FranksGuoshuai CaiBhaven K MehtaTammara A WoodKimberly ArchambaultPatricia A PioliRobert W SimmsNicole M OrzechowskiSarah T ArronMichael L WhitfieldPublished in: Arthritis research & therapy (2019)
Microbiome dysbiosis is associated with disease duration and increased inflammatory gene expression. These data provide a comprehensive portrait of the SSc skin microbiome and its association with local gene expression, which mirrors the molecular changes in lesional skin.