Heritability of Magnetoencephalography Phenotypes Among Patients With Genetic Generalized Epilepsy and Their Siblings.

Christina Stier Adham Elshahabi Yiwen Li Hegner Kotikalapudi Raviteja Justus Marquetand Christoph Braun Holger Lerche Niels K Focke

Published in: Neurology (2021)

Metrics of brain oscillations are well suited to characterize GGE and likely relate to genetic factors rather than the active disease or treatment. High power and connectivity levels co-segregated in patients with GGE and healthy siblings, predominantly in the β band, representing an endophenotype of GGE.

Keyphrases

resting state
white matter
genome wide
intellectual disability
functional connectivity
copy number
multiple sclerosis
autism spectrum disorder
smoking cessation
replacement therapy
subarachnoid hemorrhage