Beneficial effects of MgSO 4 on TFAM, UPC3 and FNDC5 mRNA expressions in skeletal muscle of type 2 diabetic rats: a possible mechanism to improve insulin resistance.

Farzaneh Yazdanimoghaddam Mahmoud Aghaei Maedeh Ghasemi Nepton Soltani Hossein Rezazadeh Fouzieh Zadhoush

Published in: Molecular biology reports (2022)

can improve insulin resistance and hyperlipidemia partly through decreasing Ox-LDL, increasing serum irisin levels as well as increasing FNDC5, TFAM, and UCP3 mRNA expressions in T2DM rats. These findings can be considered in the management of diabetes treatment.

Keyphrases

insulin resistance
skeletal muscle
diabetic rats
high fat diet
glycemic control
type diabetes
high fat diet induced
adipose tissue
metabolic syndrome
oxidative stress
polycystic ovary syndrome
binding protein