Exosomes derived from umbilical cord mesenchymal stem cells reduce microglia-mediated neuroinflammation in perinatal brain injury.
Gierin ThomiDaniel SurbekValérie HaeslerMarianne Simone Joerger-MesserliAndreina SchoeberleinPublished in: Stem cell research & therapy (2019)
Our data suggest that the administration of hWJ-MSC-derived exosomes represents a promising therapy to prevent and treat perinatal brain injury.
Keyphrases
- brain injury
- mesenchymal stem cells
- umbilical cord
- cerebral ischemia
- subarachnoid hemorrhage
- pregnant women
- bone marrow
- cell therapy
- inflammatory response
- electronic health record
- traumatic brain injury
- lipopolysaccharide induced
- big data
- lps induced
- neuropathic pain
- stem cells
- spinal cord injury
- machine learning
- spinal cord
- deep learning
- replacement therapy