The relationship between chronic kidney disease and denosumab-induced hypocalcemia in high-age osteoporotic patients.

Akira HorikawaMichio HongoYuji KasukawaYoichi ShimadaHiroyuki KodamaAkihisa SanoNaohisa Miyakoshi

Published in: Journal of bone and mineral metabolism (2022)

Advanced age combined with low eGFR and low serum Ca status appear to be associated with the incidence of hypocalcemia when using denosumab for the treatment of osteoporosis.

Keyphrases

end stage renal disease
chronic kidney disease
bone mineral density
postmenopausal women
peritoneal dialysis
small cell lung cancer
newly diagnosed
ejection fraction
prognostic factors
epidermal growth factor receptor
tyrosine kinase
high glucose
giant cell
oxidative stress
endothelial cells
replacement therapy