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CCN1 stimulated the osteoblasts via PTEN/AKT/GSK3β/cyclinD1 signal pathway in Myeloma Bone Disease.

Siyang YanHui LiuZhaoyun LiuFengping PengFengjuan JiangLijuan LiWenhui Lei
Published in: Cancer medicine (2019)
CCN1 can stimulate osteoblasts through PTEN/AKT/GSK3β/cyclinD1 pathway in MBD, which has the potential to be a novel therapy of MBD.
Keyphrases
  • pi k akt
  • signaling pathway
  • cell proliferation
  • bone mineral density
  • multiple myeloma
  • newly diagnosed
  • stem cells
  • risk assessment
  • postmenopausal women
  • climate change
  • bone marrow
  • bone loss