Elevated IgG4 serum levels in patients with cystic fibrosis.

Axelle ClercQuitterie ReynaudStéphane DuruptColette Chapuis-CellierRaphaële Nové-JosserandIsabelle DurieuJean Christophe Lega

Published in: PloS one (2017)

An elevated IgG4 serum level was frequently detected in adult CF patients and did not appear to be associated with poor lung function. We suggest that IgG4 elevation is a marker of the activation of tolerance. Its clinical significance remains to be demonstrated.

Keyphrases

cystic fibrosis
lung function
pseudomonas aeruginosa
end stage renal disease
chronic obstructive pulmonary disease
ejection fraction
chronic kidney disease
newly diagnosed
air pollution
prognostic factors
young adults