Engrailed 2 (EN2) acts as a glioma suppressor by inhibiting tumor proliferation/invasion and enhancing sensitivity to temozolomide.
Tengfei LiWanchun YangMao LiShuxin ZhangXingwang ZhouMingrong ZuoQiuyun YuanMina ChenYanhui LiuPublished in: Cancer cell international (2020)
Our data identify a novel function of EN2 in glioma suppression and provide potential therapeutic targets for glioma therapy.