Exploration of anti-inflammatory mechanism of forsythiaside A and forsythiaside B in CuSO4-induced inflammation in zebrafish by metabolomic and proteomic analyses.

Lihong GongLinyuan YuXiaohong GongCheng WangNaihua HuXuyang DaiCheng PengYun-Xia Li

Published in: Journal of neuroinflammation (2020)

Our results indicate that FA and FB possess remarkable anti-inflammatory properties, protecting against CuSO4-induced neuromasts damage in zebrafish larvae. The results also suggest a multi-component and multi-regulatory therapeutic mechanism for FA and FB.

Keyphrases

anti inflammatory
oxidative stress
diabetic rats
high glucose
drug induced
transcription factor
zika virus
label free