A neonatal murine model for evaluation of enterovirus E HY12 virus infection and pathogenicity.
Xiaochun GaiQun ZhangHaibing LuZhanqing YangLisai ZhuXin LiXinping WangPublished in: PloS one (2018)
A neonatal murine model for HY12 infection is successfully established for determining the susceptible mouse strain, the minimal infective dose, the infection route, the viral pathogenicity and the tropism of HY12, thus providing an invaluable model system for elucidating the pathogenesis of HY12 viruses and the elicited immunity.