Afferent arteriole responsiveness to endothelin receptor activation: does sex matter?

Eman Y GoharAnthony K CookDavid M PollockEdward W Inscho

Published in: Biology of sex differences (2019)

These data demonstrate that sex does not significantly influence afferent arteriole reactivity to ET receptor activation. Gonadectomy potentiated the responsiveness of the afferent arteriole to ETB-induced vasoconstriction in females, but not males, suggesting that female sex hormones influence ETB-mediated vasoconstriction in the renal microcirculation.

Keyphrases

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