Neurofilament light chain is a promising serum biomarker in spinocerebellar ataxia type 3.
Quan-Fu LiYi DongLu YangJuan-Juan XieYin MaYi-Chu DuHao-Ling ChengWang NiZhi-Ying WuPublished in: Molecular neurodegeneration (2019)
Levels of serum NfL were significantly elevated in SCA3 individuals and correlated with disease severity. Serum NfL is a promising serum biomarker of disease onset and progression, and a potential candidate biomarker of treatment response in SCA3.