Interactions between the circadian clock and TGF-β signaling pathway in zebrafish.
Hadas E SloinGennaro RuggieroAmir RubinsteinSima Smadja StorzNicholas S FoulkesYoav GothilfPublished in: PloS one (2018)
The current research provides evidence for an interaction between the TGF-β signaling pathway and the circadian clock system at the molecular and behavioral levels, and points to the importance of TGF-β signaling for normal circadian clock function. Future examination of this interaction should contribute to a better understanding of its underlying mechanisms and its influence on a variety of cellular processes including the cell cycle, with possible implications for cancer development and progression.