A Whole Methylome Study of Ethanol Exposure in Brain and Blood: An Exploration of the Utility of Peripheral Blood as Proxy Tissue for Brain in Alcohol Methylation Studies.
Shaunna L ClarkBlair N CostinRobin F ChanAlexander W JohnsonLinying XieJessica L JurmainGaurav KumarAndrey A ShabalinAshutosh K PandeyKarolina A AbergMichael F MilesEdwin van den OordPublished in: Alcoholism, clinical and experimental research (2018)
Overall, we have shown some methylation changes in brain and blood after acute EtOH administration and that the changes in blood partly mirror the changes in brain suggesting the potential for DNA methylation in blood to be biomarkers of alcohol use.