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Sodium-glucose co-transporter-2 inhibitors versus dipeptidyl peptidase-4 inhibitors and the risk of heart failure: A nationwide cohort study of older adults with diabetes mellitus.

Michael FralickMichael ColacciDeva ThiruchelvamTara GomesDonald A Redelmeier
Published in: Diabetes, obesity & metabolism (2021)
Older adults prescribed an SGLT2 inhibitor had a lower rate of heart failure hospitalization or death, and a lower rate of hypoglycaemia, but an increased rate of diabetic ketoacidosis compared to older adults prescribed a DPP-4 inhibitor.
Keyphrases
  • heart failure
  • physical activity
  • type diabetes
  • left ventricular
  • atrial fibrillation
  • cardiac resynchronization therapy
  • wound healing
  • adipose tissue
  • glycemic control
  • skeletal muscle