Positron Emission Tomographic Imaging of Tumor Cell Death Using Zirconium-89-Labeled APOMAB® Following Cisplatin Chemotherapy in Lung and Ovarian Cancer Xenograft Models.
Vasilios LiapisWilliam HsiehNicole L WittwerTessa GargettAndreas EvdokiouPrab TakharStacey E RuddPaul S DonnellyMichael P BrownAlexander H StaudacherPublished in: Molecular imaging and biology (2021)
Given that tumors, rather than normal tissues, were targeted after chemotherapy, these results support the clinical development of chDAB4 as a radiodiagnostic imaging agent and as a potential predictive marker of treatment response.