Oral Tolerance Induced by OVA Intake Ameliorates TNBS-Induced Colitis in Mice.

Lisiery N PaiattoFernanda G D SilvaJulia BierMárcia R Brochetto-BragaÁureo T YamadaWirla M S C TamashiroPatrícia Ucelli Simioni

Published in: PloS one (2017)

Our data show that the modulation of immune response induced by oral tolerance reduces the severity of experimental colitis. Such modulation may be partially attributed to the increase of Treg cells and reduction of pro-inflammatory cytokines in peripheral lymphoid organs of tolerant mice by bystander suppression.

Keyphrases

immune response
high fat diet induced
induced apoptosis
mouse model
wild type
big data
type diabetes
metabolic syndrome
insulin resistance
weight gain
inflammatory response
cell proliferation
adipose tissue
ulcerative colitis
body mass index
skeletal muscle
artificial intelligence